I know heroin does for sure. Any others?

You don't need to turn to drugs to lose weight.....

Depends on your term of "drugs". Prescription or illegal substances.
Since the member above mentioned crack, I do agree on that one too. There is also meth.
I disagree on wee though, take a look at Snoop Dogg. He is by far fat.
In the end, not matter what you take. It is about the diet. If I eat like a pig, and take a pill. It will not do anything.

crack
weed makes u gain weight